Clinical Trials
Evidence-based nutrition protocols developed at the KNU Veterinary Medical Teaching Hospital
From Bench to Bedside
Our clinical trials program operates at the intersection of molecular research and real-world veterinary practice. Conducted at the KNU Veterinary Medical Teaching Hospital (VMTH), each trial is designed to generate practice-changing evidence for the management of chronic diseases where nutrition plays a central therapeutic role.
All trials integrate BCS/MCS monitoring, standardized dietary assessment, and biomarker tracking — ensuring that nutritional interventions are evaluated with the same rigor applied to pharmacological treatments.
Active Research Trials
Chronic Kidney Disease (CKD)
- › Evaluate phosphorus-restricted diet efficacy across IRIS CKD stages 2–4
- › Monitor SDMA, creatinine, and UPC ratio as nutritional response markers
- › Compare protein source (plant vs. animal) effects on uremic toxin load
Oncology & Cancer Cachexia
- › Assess muscle mass preservation (MCS) under high-fat, moderate-protein diets in tumor-bearing dogs
- › Evaluate omega-3 fatty acid (EPA/DHA) supplementation on inflammatory cytokine profiles
- › Develop cachexia grading and nutritional intervention criteria for veterinary oncology
Food Allergy & Adverse Food Reactions
- › Conduct prospective elimination diet trials with novel and hydrolyzed protein sources
- › Track gut microbiome shifts during dietary elimination and rechallenge phases
- › Establish breed-specific antigen sensitivity profiles using serum IgE panels
Clinical Guideline Development
Findings from our trials are synthesized into evidence-based clinical nutrition guidelines, providing veterinary practitioners with actionable, species-specific recommendations.
CKD Nutrition Guidelines
In preparation
Oncology Nutrition Protocol
In preparation
Food Allergy Elimination Guide
Coming soon